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MAL-amido-PEG2-Val-Cit-PAB-PNP


MAL-amido-PEG2-Val-Cit-PAB-PNP

Catalog:CDPB-041351

INQUIRY Datasheet

Common UseLinker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility.
Structure MAL-amido-PEG2-Val-Cit-PAB-PNP
PEG Molecular Weight854.9 g/mol
Functional GroupMaleimide/PNP
Purity98%
Storage-20°C
Molecular FormulaC39H50N8O14
CAS No.2112738-13-1
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