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Azido-PEG4-Val-Cit-PAB-OH


Azido-PEG4-Val-Cit-PAB-OH

Catalog:CDPB-041353

INQUIRY Datasheet

Common UseLinker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility.
Structure Azido-PEG4-Val-Cit-PAB-OH
PEG Molecular Weight652.8 g/mol
Functional GroupAzide/Hydroxyl
Purity96%
Storage-20°C
Molecular FormulaC29H48N8O9
CAS No.2055024-64-9
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