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Azido-PEG3-Val-Cit-PAB-PNP


Azido-PEG3-Val-Cit-PAB-PNP

Catalog:CDPB-041354

INQUIRY Datasheet

Common UseLinker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility.
Structure Azido-PEG3-Val-Cit-PAB-PNP
PEG Molecular Weight773.8 g/mol
Functional GroupAzide/PNP
Purity95%
Storage-20°C
Molecular FormulaC34H47N9O12
CAS No.2055047-18-0
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