Azido-PEG3-Val-Cit-PAB-PNP


Azido-PEG3-Val-Cit-PAB-PNP

Catalog:CDPB-041354

Unit Size:50 mg, 100 mg, 250 mg, 1 g

INQUIRY Datasheet

Common Use Linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility.
Structure Azido-PEG3-Val-Cit-PAB-PNP
PEG Molecular Weight 773.8 g/mol
Functional Group Azide/PNP
Purity 95%
Molecular Formula C34H47N9O12
CAS No. 2055047-18-0
Storage -20°C

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