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Clipos™ DiR Labeled Phosphatidylcholine (PC) Liposomes, PEGylated

Catalog:CDL6002F-DR

Unit Size
Price
$1080

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Specifications QA & Reviews
Storage2-8 °C
DescriptionThe fluorescent control liposomes contain the lipophilic Near IR dye DiR incorporated in the bilayers. It is used for tracking the cellular uptake of the liposomes in vitro and in vivo by common methods like confocal, FACS, NIR imaging etc. The near IR fluorescent, lipophilic carbocyanine DiOC18(7) ("DiR") is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. The sulfonate groups incorporated into this DiI analog improves water solubility. It has an extremely high extinction coefficient and short excited-state lifetimes (~1 nanosecond) in lipid environments.
Lipid compositionDOPC/Cholesterol/mPEG2000-DSPE (50/45/5 molar ratio)
Liposome Size100 nm (85-110 nm)
Lipid Molar Concentration50 mM (50-55 mM)
FluorophoreDiR
Fluorophore Concentration0.5 mM (0.51 mg/mL)
Excitation750 nm
Emission780 nm
Buffer10% sucrose, 20mM HEPES, pH 7.5 ± 0.2
Shelf-life6 month for unopen vials
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