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Clipos™ Saturated Phosphatidylcholine (PC) Liposomes, Lyophilized

Catalog:CDELHP-1233

Unit Size

10 mg

Price: $2100

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Specifications QA & Reviews

Storage	Should always be stored in a freezer at at -40 °C or -80 °C. Upon adding water to proliposomes, liposomes are formed.
Appearance	White lyophilized powder. Liposomes are formed upon adding water to the freeze dried proliposomes and the appearance of the formulation will be white translucent liquid.
Lipid composition	19/0 PC/Cholesterol (70/30 molar ratio)
Liposome Size	100 nm (after hydration)
Buffer	Lyophilized Phosphate Buffered Saline, 7.4 (after hydration)
Shelf-life	6 months.
Technical Notes	Liposomes are formed upon hydration of the lyophilized formulation. If the lyophilized liposomes are hydrated with solution containing a water soluble drug then a large percentage of the drug will stay outside of the liposomes and in non-encapsulated form. It is advised to use a micro dialysis cassette or a spin column using the right side beads (depending on the size of your drug) and separate the drug encapsulated liposomes from free drug and perform the drug assay in order to calculate the encapsulation efficiency. Lyophilized liposomes are mainly recommended to be used with drugs that have a short life in aqueous solution mainly due to hydrolysis. After adding the solution of the drug to lyophilized liposomes, the liposomes should be used immediately. Lyophilized Liposomes products should be used by scientists who understand liposome formulation and have the proper equipment in order to check the size, separate the non-encapsulated drug and do the proper assays. Trehalose is used as a lyoprotectant in all freeze dried liposome formulation. The size distribution after hydration of the freeze dried formulation will be around 100 nm.

Related Products

Product Name	Catalog	Lipid composition	Liposome Size	Price
Clipos™ Saturated Phosphatidylcholine (PC) Liposomes, Lyophilized	CDECDEE-1617	13/0 Diether PC/Cholesterol (70/30 molar ratio)	100 nm	$2100
Clipos™ Saturated Phosphatidylcholine (PC) Liposomes, Lyophilized	CDECUP-1548	100% 18/0-18/2 PC	100 nm	$2100
Clipos™ Saturated Phosphatidylcholine (PC) Liposomes, Lyophilized	CDELHP-1216	100% 17/0 PC	100 nm (after hydration)	$2100
Clipos™ Saturated Phosphatidylcholine (PC) Liposomes, Lyophilized	CDECUP-1542	100% 22/1 (Cis) PC	100 nm	$2100
Clipos™ Saturated Phosphatidylcholine (PC) Liposomes, Lyophilized	CDEPG-30	DMPC/Chol/DSPE-mPEG2000 (50/45/5 molar ratio)	70-120 nm	$1200
Clipos™ Saturated Phosphatidylcholine (PC) Liposomes, Lyophilized	CDELUP-1210	100% 18/1-14/0 PC	100 nm (after hydration)	$2100
Clipos™ Saturated Phosphatidylcholine (PC) Liposomes, Lyophilized	CDECHP-1573	15/0 PC/Cholesterol (70/30 molar ratio)	100 nm	$2100
Clipos™ Saturated Phosphatidylcholine (PC) Liposomes, Lyophilized	CDL1003	DOPC	100 nm (90-120 nm)	$1200

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