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Clipos™ Doxorubicin Encapsulated Liposomes, PEGylated

Catalog:CDEDOX-1014

Unit Size
Price
$1200

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Specifications QA & Reviews
Functional GroupPlain
StorageShould always be stored at in the dark at 4 °C, except when brought to room temperature for brief periods prior to animal dosing. DO NOT FREEZE. If the suspension is frozen, the encapsulated drug can be released from the liposomes thus limiting its effectiveness. In addition, the size of the liposomes will also change upon freezing and thawing.
AppearanceThe product is a red translucent liquid made of nano size unilamellar liposomes. Usually due to the small size of liposomes no settling will occur in the bottom of the vial. The liposomes are packaged in an amber vial.
DescriptionThis formulation of doxorubicin liposomes is PEGylated. The formulation is for research purposes only and for the injection to laboratory animals. Doxorubicin drug is already loaded into the liposomes using remote loading by ammonium sulfate gradient. The formulation is ready for injection.
Lipid compositionHSPC/Cholesterol/DSPE-PEG(2000) (57/38/5 molar ratio)
Liposome Size80-100 nm
Lipid Molar Concentration21.62 mM
Shelf-life4 months.
Encapsulated DrugDoxorubicin
Lipid Mass Concentration15.96 mg/mL
Drug concentration2 mg/mL (3.45 mM)
Inside BufferAmmonium Sulfate, pH 6.5
Outside BufferHistidine/Sucrose Buffer, pH 6.5
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