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Clipos™ Topotecan Encapsulated Liposomes, PEGylated


Catalog:CDL3001-TT

Unit Size
Price
$2200

Buy Now Datasheet Need technical support?

Storage2-8 °C
DescriptionTopotecan HCl is loaded into PEGylated liposomes composed of HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) with ammonium sulfate gradient by the active loading approach. The liposomes are produced by the extrusion method. The product is of high quality with Narrow particle size distribution and high drug encapsualtion efficiency.
Lipid compositionHSPC/Cholesterol/mPEG2000-DSPE (50/45/5 molar ratio)
Liposome Size100 nm (80-110 nm)
Lipid Molar Concentration20.0 mM
Shelf-life3 months
Encapsulated DrugTopotecan HCl
Drug concentration2.0 mg/mL
Outside Buffer10% sucrose, 20 Mm HEPES, pH 7.0
Encapsulation efficiency> 95%
Loading Battery250 mM ammonium sulfate
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