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Clipos™ Doxorubicin HCl Encapsulated Liposomes, PEGylated, High Potency

Catalog:CDL3001B-D

Unit Size
Price
$1200

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Specifications QA & Reviews
Functional GroupPlain
Storage2-8 °C
DescriptionDoxorubicin HCl is loaded into PEGylated liposomes composed of HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol) with ammonium gradient by the active loading approach.  The liposomes are prepared to very high quality with consistent lot-lot characteristics. Narrow particle size distribution and high drug encapsulation efficiency.
Lipid compositionHSPC/Cholesterol/mPEG2000-DSPE (56.2/38.5/5.3 molar ratio)
Liposome Size85 nm (80-90 nm)
Lipid Molar Concentration40.0 mM
Shelf-life6 months
Encapsulated DrugDoxorubicin HCl
Drug concentration4 mg/mL
Outside Buffer10% sucrose, 10 mM histidine, pH 6.5
Encapsulation efficiency> 95% (typically 98%)
Loading Battery250 mM ammonium sulfate
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