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Clipos™ Control of Neutral Clodronate Encapsulated Liposomes, DiR Labeled

Catalog:CDL7001FR-N

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Price
$695

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Specifications QA & Reviews
Storage2-8 °C
DescriptionThe fluorescent control liposomes contain the lipophilic dye DiR incorporated in the bilayers. It has comparable physical and chemical attributes as for the Clodronate Encapsulated Liposomes except no clodronate encapsulated inside. It is used for tracking the cellular uptake of the liposomes by common methods like confocal, FACS, NIR imaging etc. The near IR fluorescent, lipophilic carbocyanine DiOC18(7) ("DiR") is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. The sulfonate groups incorporated into this DiI analog improves water solubility. It has an extremely high extinction coefficient and short excited-state lifetimes (~1 nanosecond) in lipid environments.
Lipid compositionPC/Cholesterol
FluorophoreDiR
Fluorophore Concentration0.15 mM (0.15 mg/mL)
Excitation750 nm
Emission780 nm
Shelf-life6 months for unopened vials
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