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Clipos™ Control of Anionic Clodronate Encapsulated Liposomes, DiD Labeled

Catalog:CDL7001FD-A

Unit Size
Price
$695

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Specifications QA & Reviews
Storage2-8 °C
DescriptionThe fluorescent control liposomes contain the lipophilic dye DiD incorporated in the bilayers. It has comparable physical and chemical attributes as for the Clodronate Encapsulated Liposomes except no active is encapsulated inside. It is used for tracking the cellular uptake of the liposomes by common methods like confocal, FACS, etc. The far-red fluorescent, lipophilic carbocyanine DiD is a longer-wavelength DiI analog. It is an oil at room temperature and weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. It has an extremely high extinction coefficient and short excited-state lifetimes (~1 nanosecond) in lipid environments.
Lipid compositionPC/PG/Cholesterol
Liposome Size100 nm (90-120 nm)
Lipid Molar Concentration50 mM (50-55 mM)
FluorophoreDiD
Fluorophore Concentration0.15 mM (0.14 mg/mL)
Excitation644 nm
Emission665 nm
Buffer10% sucrose, 20mM HEPES, pH 7.5 ± 0.2
Shelf-life6 months guaranteed for unopened vials.
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