Thiol-Modified Hyaluronan/Heparin Mixture

Catalog:CDAD30

Unit Size

Price: $720

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Description

A mixture of thiol-modified hyaluronic acid thiol-modified heparin, is a component of the Thiol-Modified Hyaluronan, Gelatin and Heparin Hydrogel Kits, but can be purchased separately here. Hyaluronic acid is a major constituent of native extracellular matrix (ECM). Heparin is also present in the ECM as heparan sulfate. Most cells do not attach to Heprasil-only hydrogels. Heprasil must be used in conjunction with thiol-modified gelatin or ECM proteins such as laminin, collagen, or fibronectin for most 3-D cell culture and tissue-engineering applications. For gelation, reconstituted Heprasil remains liquid at 15 to 37°C. Without a crosslinker, Heprasil will form a hydrogel via disulfide bond formation; however, the gelation time is over twenty-four hours. If PEGDA is used to crosslink the Heprasil, the gelation time is about twenty minutes with no low-temperature or low-pH steps. Diluting Heprasil with phosphate-buffered saline (PBS) or cell-culture medium can increase its gelation time. This product is for R&D use only and is not intended for human or other uses.

Form

Lyophilized Powder

User Manual_Thiol-Modified Hyaluronan-Heparin Mixture, CDAD30

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