Cell-degradable polyethylene glycol peptide conjugate which contains a Matrix-Metallo-protease cleavable peptide, allowing the cell to cleave the crosslinker to spread and migrate within the gel. 3CG-Link (20 mmol/L thiol groups) contains the peptide sequence Pro-Leu-Gly-Leu-Trp-Ala, which is known to be cleaved by matrix metalloproteases, such as MMP1, MMP3, MMP7 or MMP91. Allows formation of 1 mL 3D Cell Culture Hydrogel, crosslinked with 4 mmol/L maleimide groups. Intended for research use only. Not for use in human therapeutic or diagnostic applications.
Storage
-20°C to -80°C
Form
Lyophilized Powder
Sterilization Method
Filtration
Applications Note
Be used together with Maleimide-PVA or Maleimide-Dextran to establish 3-D cell cultures in biomimetic hydrogels.