Polycaprolactone (PCL) is a degradable synthetic polymer material formed by ring-opening polymerization of ε-caprolactone under the catalysis of metal anion complex catalysts. It is insoluble in water, but soluble in various organic solvents; it can be completely degraded into carbon dioxide and water in the natural environment, and the degradation products can be absorbed or excreted by the body, and its good biocompatibility makes it widely used in medicines controlled-release. And it has cytocompatible with some tissues of the human body, so it is also an ideal material for tissue engineering. However, PCL itself has limitations such as long degradation cycle and poor hydrophilicity. In order to improve this limitation and broaden its application range, researchers often change the properties (such as hydrophilicity, solubility, degradability, etc.) of the material by physically blending or chemically modifying PCL. At the same time, by using a variety of molding methods to obtain drug controlled-release carriers with different structural characteristics to meet different drug loading needs.
CD Bioparticles offers polycaprolactone polymers of different molecular weights for use in drug discovery research. In addition, we also offer polycaprolactone polymers modified with acid, cholesterol, ester, hydrazide and hydroxyl groups.
