Aptamer and Organic Nanocarrier Coupling Service
Aptamer-mediated targeted drug delivery can be used to treat a wide range of diseases, including oncology, immune diseases, genetic diseases, infectious diseases, and cytopathic diseases. By modifying the targeting ligands on the surface of drug carriers to improve the ability of drug carriers to actively target into cells, the drug can be effectively released into the target cells, thus greatly improving the drug efficacy.
CD Bioparticles has many years of experience in developing drug delivery aptamers, and our scientists are confident to provide you with a one-stop service for coupling aptamers with organic nanocarriers to facilitate the development of drug targeting delivery research. We provide customized aptamer-nanocarrier coupling services for targeted drug delivery system research.
Aptamer and Organic Nanocarrier Coupling Service Background
Aptamers are considered as chemical antibodies that can be easily coupled to drugs, sensors, signal enhancers or nanocarriers for functionalization.
Aptamers are flexibly coupled to various nanocarriers by various coupling methods. For example, organic nanocarriers (liposomes, polymer-lipid hybrid NPs, micelles, and dendrimers) can be modified with specific aptamers to enable targeted drug delivery. Organic nanomaterials are promising for nano-delivery systems due to their good biocompatibility and degradability.
Fig. 1 Representative examples of various traditional nanomaterials studied for cancer theranostic applications.
(S Nem, et al., 2023)
Our Aptamer and Organic Nanocarrier Coupling Services
CD Bioparticles specializes in the development of drug-targeted delivery aptamers and uses our core technology to enable coupling services between aptamers and organic nanocarriers. With our high quality services, you can greatly improve the progress of your experimental studies.
Our team can provide services from aptamer screening to aptamer-organic nanocarrier coupling for drug delivery system research, and we can customize experimental protocols according to customer needs. The aptamer-organic nanocarrier drug delivery systems we offer include but are not limited to the following.
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Aptamer-liposome drug delivery systems
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Aptamer-polymer micelle drug delivery systems
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Aptamer-polymer nanoparticle drug delivery systems
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Aptamer-metal particle drug delivery system
In addition, particle properties such as component molecular weight, surface charge and charge density, solubility and hydrophobicity can be designed to your liking.
Advantages of Organic Nanocarriers
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Organic nanocarriers are versatile
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Organic nanocarriers are less toxic
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Organic nanocarriers can bind a wide range of drugs and drug delivery ligands
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Capability to accumulate at desired sites through strong permeability and retention for micellar and liposome-mediated drug delivery
Service Users
Our services are dedicated to providing in-depth and professional services to practitioners in the biomedical technology industry, such as universities, research institutions, and biotechnology companies.
Quotations and Ordering
If you are interested in our services, please do not hesitate to contact us for more detailed information.
Reference
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S Nem, Kim J, et al. Covalent organic framework nanomedicines: Biocompatibility for advanced nanocarriers and cancer theranostics applications. Bioact Mater. 2023; 21: 358-380.
