-
Injection Nano Drug Delivery System II
As mentioned above, liposomes, microemulsions and nanoemulsions are used for pharmaceutical transportation through the injection of nanometer drug delivery system. And this article will further introduce other nano-carriers that can be administered by injection nano-administration, including: nanoparticles, polymer micelles, nanogels, polymer complexes, and nanosuspensions. Nanoparticles Nanoparticles, as a carrier for the injection of nano-drug delivery systems, have their advantages mainly in: 1. The more hydrophilic the surface of the surface-modified nanoparticles, the smaller the uptake by macrophages. 2. The in vitro release of drugs can be adjusted by controlling the increase in PEG molecular weight and content or the decrease in copolymer molecular weight. 3. The distribution of nanoparticles in…
-
Injection Nano Drug Delivery System 1
Injection administration is to inject drugs into the body through injection to achieve the purpose of preventing and treating diseases. There are three ways of injection administration: intravenous (IV), intramuscular (IM) and subcutaneous (SC). Each has its own advantages and disadvantages. Different injection methods should be selected according to the specific situation. Liposomes Liposomes are vesicles sealed by a bilayer of phospholipids, similar to the cell structure, with an internal aqueous phase that can encapsulate water-soluble drugs. The inside of the lipid bilayer is fat-soluble and can encapsulate fat-soluble drugs, but the capacity is limited. According to the particle size, liposomes can be divided into small unilamellar vesicles (SUV, 30~100nm),…