Targeted drugs were proposed by German scientist and Nobel Prize winner Ehrlich in 1906 and have a history of more than 100 years. Until the late 1970s, with the advancement of molecular biology, cell biology, and materials science, targeted formulations developed rapidly, and products began to be marketed. The nano drug delivery system is distributed in specific organs, tissues, cells, and even intracellular structures in the body through passive targeting, active targeting, physical and chemical targeting, etc., and changes the distribution of prototype drugs in vivo. With the leapfrog development of life sciences, human understanding of disease pathogenesis and drug action mechanisms has transitioned from a macroscopic overall level to…