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Cell Membrane Biomimetic-Based Drug Delivery Systems


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CD Bioparticles is a supplier specializing in cell membrane biomimetic systems. We provide you with customized cell membrane biomimetic nanosystems based on the effect of action.

CD Bioparticles is a leading global supplier of cell membrane biomimetic with a dedicated research team and strong technical capabilities. Cell membrane biomimetic have versatility and great potential in the field of drug delivery. They play an important role in improving drug biocompatibility, enhancing long-lasting circulation and biotargeting delivery. Cell membrane biomimetic technology is not only limited to erythrocyte membranes, but also includes, leukocyte membranes (e.g., macrophage, neutrophil, and T-cell membranes), platelet membranes, and cancer cell membranes. These different cell membrane types offer the possibility of treating a wide range of diseases, such as platelet membranes for atherosclerosis and restenosis, and immune cell membranes for immune disorders. Cell membrane bionanomics customization technology provides a new strategy and platform for drug delivery, tissue engineering, and disease treatment by mimicking the structure and function of natural cell membranes. CD Bioparticles can help you to solve a series of tricky problems based on cell membrane biomimetic with one-to-one customization service.

Today we offer you:

With the advancement of DDS development, the professional researchers at CD Bioparticles have achieved significant research results in the field of cell membrane bionic delivery systems. We can provide you with a variety of services related to cell membrane-based drug delivery systems to meet your research needs.

  • Cell membrane biomimetic customization services
  • Analysis in vivo and in vitro including targeting, toxicity and pharmacokinetics

Table of Contents

  • Advantages of cell membrane biomimetic
  • List product of cell membrane biomimetic

Advantages of Cell Membrane Biomimetic

  • Improved biocompatibility and low immunogenicity

Cell membrane biomimetic nano drug delivery system has the advantages of biocompatibility and low immunogenicity, which can improve the safety of treatment and minimize the side effects.

  • Long circulation and targeted delivery

Natural cell membrane encapsulated nanoparticles have both the physical and chemical properties of the nanoparticles themselves and the biological properties of the cells, which prolongs the half-life of drug action. Meanwhile, macrophage membrane and cancer cell membrane modified nanoparticles have homologous targeting ability. It can be used for highly specific cancer targeting and effective cancer therapy.

  • Evade recognition and clearance by the immune system

By modifying the surface of nanoparticles with natural cell membranes, immune evasion and extended circulation time in the body have been achieved, thereby providing an effective biomimetic camouflage effect. This has allowed for the avoidance of immune system recognition and clearance.

Part of Cell Membrane Biomimetic Products

CatalogProducts 
CDCM24-001-LFe3O4-LMNVs, Leukocyte membrane-coated Fe3O4
CDCM24-003-LEBPQD-EMNVs, Rythrocyte membrane-encapsulated BPQD
CDCM24-006-LFA-PEG-MNVs, FA-PEG modified cell membranes
CDCM24-010-LPDA@DOX-SMNVs, Stem cell membrane-encapsulated PDA@DOX
CDCM24-020-LDOX-MCF-7 CMVs, MCF-7 cell membrane-encapsulated DOX
CDCM24-021-LRVG29-MMNVs, Macrophage membrane modification RVG29
CDCM24-023-LZnO-MNVs, Cell membrane-coated ZnO
CDCM24-024-LGelatin-MNVs, Cell membrane-coated gelatin
CDCM24-027-LPEI-EMNVs, Erythrocyte membrane-coated PEI
CDCM24-034-LDrugs-ECMNVs, Epithelial cell membrane-encapsulated Drugs
CDCM24-037-LGYRCDS-OMNVs, Osteoblast membrane modification GYRCDS peptide
CDCM24-038-LBSA-FMNVs, Fibroblast membrane-coated BSA
CDCM24-041-LLiposomes-MMNVs, Macrophage membrane-coated liposomes
CDCM24-043-LCeO2-EMNVs, Erythrocyte membrane-coated CeO2
CDCM24-045-LPLGA-MNMNVs, Melanoma cell membrane-coated PLGA
CDCM24-048-LAu-PCMNVs, Primary cell membrane-coated Au
CDCM24-050-LUCNPs-PCMNVs, Primary cell membrane-coated UCNPs

    References

  1. Liu W, et al.; Light-triggered biomimetic nanoerythrocyte for tumor-targeted lung metastatic combination therapy of malignant melanoma. Small. 2018, 4: 1801754-1801768.
  2. Wei X, et al.; A stepwise targeting and antibacterial strategy by leukocyte membrane-based conjugated oligomer nanoparticles. ACS Appl. Bio Mater. 2023, 6: 2487-2495.
  3. Wang P, et al.; Cancer cytomembrane-cloaked prussian blue nanoparticles enhance the efficacy of mild-temperature photothermal therapy by disrupting mitochondrial functions of cancer cells. ACS Appl. Mater. Interfaces. 2021, 13: 37563-37577.
  4. Wei XL, et al.; Nanoparticle functionalization with platelet membrane enables multifactored biological targeting and detection of atherosclerosis. ACS Nano. 2018, 12: 109-116.
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