Liposome System

CD Bioparticles’ products with customized delivery strategies, precise designs and modifications of drugs or drug-contained cargos, and advanced technical platforms can help you to solve:

The challenges you might meet:

• Limited options of drug-loaded or non-loading liposomes for positive control and negative control of your drug delivery tests or exosome studies
• Complicated formulation of lipid composition and ratio to prepare artificial cell models
• Hard to incorporate active biomolecules, such as peptide, antibody, protein, nucleic acid, and polysaccharide on the surface of the liposomes
• Limited options for tracking and detection of fusion, pore forming, and cell uptake (e.g. macrophage) experiments
• Hard to track and image the distribution of the liposomes
• Tedious chemical synthesis, formulation, and purifications

Figure 1. Schematic representation of the classification of different liposomes.

Plain Liposomes Key features:

• Plain Liposomes

  • DOTAP-based Cationic Liposomes

  • Total Lipid Liposomes from Natural Lipid Extracts

  • Phosphatidylserine (PS) Liposomes

  • Cardiolipin Lipids (CL) Liposomes

  • Phosphatidylcholine (PC) Liposomes

  • Phosphatidylglycerol (PG) Liposomes

• Reactive Liposomes

  • Folate Liposomes

  • Cyanur Liposomes

  • Succinyl Liposomes

  • Glutaryl Liposomes

  • Amine Liposomes

  • Carboxylic Acid Liposomes

  • Metal Chelating Liposomes: Ni Reactive Liposomes:

  • Biotinylated Liposomes

  • Dodecanyl Liposomes:

  • Azide Liposomes

  • DBCO Liposomes

  • PDP Liposomes: Sulfhydryl Reactive Liposomes

• Magnetic Liposomes

• Fluorescent Liposomes

  • Fluorescent Plain Liposomes

  • Fluorescent Reactive Liposomes

  • Fluorescent Drug Loaded Liposomes

  • Fluorescent Liposomes for DNA/RNA Delivery

  • Wide coverage of the Fluorescent options

• Drug Loaded Liposomes

  • Liposomal ATP

  • Liposomal DOTA

  • Liposomal Topotecan

  • Liposomal Clodronate

  • Liposomal Doxorubicin

  • Liposomal Alendronate

• Liposomes for Cosmetics

  • Resveratrol

  • THC

  • Vitamin A Palmitate

  • Vitamin C

  • Curcumin

  • Alpha Lipoic Acid

  • Vitamin A, E & K

  • Coenzyme Q10

  • Azelaic Acid

  • Soy Isoflavones

  • Phenylethyl Resorcinol

  • Vitamin E

  • Ferulic acid

  • Phytosterol

  • Lutein

  • Salicylic acid

  • Retinaldehyde

  • Ceramide

• API loaded Liposomes

  • Food additives

    • Vitamine A liposomes
    • Alpha lipoic acid (ALA) liposomes
    • Curcumin liposomes
    • AEK liposomes
    • HK20 liposomes
    • Ferulic Acid liposomes
    • Asta liposomes
    • Q10 liposomes
    • Resveratrol liposomes
    • Lutein liposomes
    • Vitamine E liposomes
    • ISO (Estradiol) liposomes
    • Vitamine C liposomes

  • Cosmetic additives

    • 4-Hexylresorcinol liposomes
    • Retinol liposomes
    • Idebenone liposomes
    • r-Retinoate liposomes
    • Liposomal o-Cymen-5-OL
    • Liposomal Asta
    • Liposomal Resveratrol
    • Liposomal THC
    • Liposomal Vitas
    • Liposomal Pterostilbene
    • Liposomal Gallic acid
    • Natural Soluble Yeast Beta-Glucan
    • Phytosterol liposomes
    • Azelaic liposomes
    • Liposomal 377
    • 5-amino-4-oxovaleric acid
    • Galla Rhois Gallnut Extract Nanoemulsion
    • Salicylic Acid liposomes
    • Anti-acne concentrates liposomes

• Liposomes for DNA/RNA Delivery

  • DDAB Liposomes for DNA/RNA Delivery

  • GL-67 Liposomes for DNA/RNA Delivery

  • DOTMA Liposomes for DNA/RNA Delivery

  • DOTAP Liposomes for DNA/RNA Delivery

  • DODAP Liposomes for DNA/RNA Delivery

  • DC-Cholesterol Liposomes for DNA/RNA Delivery

Plain Liposomes Key benefits:

• Wide coverage of the functional liposomes
• Cell-membrane mimic liposomes
• Multi-functional-group useful for further conjugation and crosslinking, good for further conjugation, labeling, targeting
• Wide coverage of fluorescent lipophilic tracer for tracking and detection of the liposomes
• Precise control of the fluorophore substitution, well-control of the intensity-concentration dependence
• Optimized liposome composition improving transfection efficiency and stability
• Fluorescent cationic liposome useful tracking and imaging of the transfection
• Post PEGylation useful for optimizing the PEG ratio
• Pre-loaded API liposomes useful for various of formulations and studies
• Ready-to-use

Plain Liposomes Application candidates:

• Control formulations for many different types of drug encapsulated liposome formulations.
• Artificial cell models
• Charged liposomes useful in many different types of blood complement studies
• Tracking and imaging of the transfection
• DNA/RNA delivery
• Fusion experiments of two separate membranes.
• Tracking and detection of cell uptake (e.g. macrophage)
• Long circulation applications
• Experiments that involve pore formation and disruption of the membrane, to study pore formation or disruption by external factors such as detergents, peptides, etc.