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Transfection


Transfection facilitates the study and control of gene function in eukaryotic cells. It can be carried out using calcium phosphate (tricalcium phosphate), by electroporation, by cell squeezing, or by mixing a cationic lipid with the material to produce liposomes that fuse with the cell membrane and deposit their cargo inside. Transfection technology has been widely used in biological experiments to study gene function, regulatory gene expression, mutation analysis, and protein production.

With the development of gene and protein function, transfection has become a fundamental method in laboratory work. CD Bioparticles' services with customized delivery strategies, precise designs and modifications of drugs or drug-contained cargos, and advanced technical platforms can help you to solve:

The challenges you might meet:

  • The transfection rate is low
  • The expression time of genes is shorter
  • Longer gene sequences cannot be transfected
  • The cytotoxicity of transfection vector is high
  • Poor quality transfection material in the project
  • Tedious synthesis and production

Schematic illustration of cell transfectionFigure 1. Schematic illustration of cell transfection.

Key features:

Key benefits:

  • Lower cytotoxicity and damage
  • Wide coverage of the transfection systems for customized product development
  • High purity materials are developed for pharmaceutical products
  • Customized synthesis and production
  • From raw materials to customized kits and analysis services providing full services of your transfection related studies
  • GMP promises the quality of products

Application candidates:

  • As a bioreactor to produce medicinal proteins
  • Gene therapy for rare cancers
  • Expression and production of medical protein and antibody
  • Useful for drug delivery in vivo
  • Building animal models of disease and drug screening models
  • Xenotransplantation of organs
  • Improving plant and animal species and performance
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