Viral Vector-Based Delivery System

• VSV Vectors
• Retroviral Vectors
• Lentiviral Vectors
• HSV Vectors
• Adenovirus Vectors
• Adeno-Associated Virus Vectors

CD Bioparticles offers custom services to characterize viral vector-based gene therapy and drug delivery system using advanced gene edition techniques. Our experienced scientists and technicians have created a comprehensive platform to measure the validity and efficiency of different viral vector drug delivery system.

Introduction of Viral Vector-Based Delivery System

Compared to the physical or chemical methods-based delivery route of non-viral vector, viral vectors apply the noncontagious virus blueprints for genetic materials delivering into cells and organs. With the partial virus characters, viral vectors efficiently and precisely reach the target tissue/cell. The delivery system can be used to express protein/antigen and foreign therapeutic gene for vaccine and cancer therapy. Adenoviruses (AdV), adeno-associated viruses (AAV), Retroviruses and lentiviruses are the mainly used viral vectors for the of the external gene. Herpes simplex virus (HSV), Rabies virus (RV), and Vesicular stomatitis virus (VSV) are widely used in neuroscience research due to their neurotropism^[1].

Since FDA approval, viral vectors have become a popular choice in the field of gene therapy, cancer therapy and vaccine.

Figure 1. Viral vector-based gene therapy.

We offer a variety of virus vector drug delivery systems. Please click on the different virus vector types to obtain more information on targeted viral vector.

CD Bioparticles offers design, synthesis, packaging, characterization, and evaluation services for drug delivery systems based on different types of virus vectors, including virus vector modifications for CAR-T, CAR-NK therapies, and oncolytic virus products. Our team is dedicated to supporting your research objectives by improving viral load, regulating the types of cells being infected, increasing the stability of exogenous gene expression, reducing the immunogenicity, and enhancing targeting. In addition, we are able to deliver reliable and scalable production specialized from upstream expression to downstream production, isolation, and purification with strict quality control.

The specific features of virus vectors include:

• Higher delivery efficiency
• More precise targeting
• More mature technology
• Relatively modifiable immunogenicity

Several types of virus vectors are available, each with distinct functional properties. In order to ensure optimal results, it is crucial to have a comprehensive comprehension of the attributes of different tissues and cells and thoughtfully select an appropriate virus vector as the delivery agent. Our team is committed to offering you the most dependable technical support that aligns with your specific experimental objectives.

Quotations and Ordering

Reference

1. Bulcha JT, et al.; Viral vector platforms within the gene therapy landscape. Signal Transduct Target Ther 2021, 6(1):53.