Storage | 2 °C to 8 °C (do not freeze), protect from light |
CAS No. | 84573-16-0 |
Description | PEGylated liposomes containing Rocaglamide (Roc-A). Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective HSF1 activation inhibitor (IC50 ~50 nM). Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also exhibits anti-leukemia activity. Rocaglamide is insoluble in aqueous media. This product is a pre-formulated liposomal version of Rocaglamide which is supplied ready to use in vitro or in vivo. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only. |
Lipid composition | PEGylated Liposomes |
Liposome Size | 70-120 nm |
Lipid Molar Concentration | 60 mM |
Shelf-life | At least 1 month |
Encapsulated Drug | Rocaglamide |
Drug concentration | 4.0 mg/mL (± ~5%) |
Inside Buffer | 292 mM sucrose, 0.5% DPBS (1X) |
Outside Buffer | 292 mM sucrose, 0.5% DPBS (1X) |
Product Name | Catalog | Lipid composition | Liposome Size | Price |
---|---|---|---|---|
Clipos™ Rocaglamide Encapsulated Liposomes | CDEPG-25 | PEGylated Liposomes | 70-120 nm | $4500 |
Clipos™ Rocaglamide Encapsulated Liposomes | CDEPG-23 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Rocaglamide Encapsulated Liposomes | CDEPG-24 | PEGylated Liposomes | 70-120 nm | $4500 |
Clipos™ Rocaglamide Encapsulated Liposomes | CDEPG-03 | PEGylated liposomes | 70-120 nm | INQUIRY |
Clipos™ Rocaglamide Encapsulated Liposomes | CDEPG-31 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Rocaglamide Encapsulated Liposomes | CDEPG-33 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Rocaglamide Encapsulated Liposomes | CDEPG-19 | HSPC/Chol/DSPE-mPEG2000 (56.2/38.5/5.3 molar ratio) | 70-120 nm | $2200 |
Clipos™ Rocaglamide Encapsulated Liposomes | CDEPG-27 | PEGylated Liposomes | 70-120 nm | $4500 |
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