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Clipos™ Rocaglamide Encapsulated Liposomes


Catalog:CDEPG-21

Unit Size
Price
$2300

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Storage2 °C to 8 °C (do not freeze), protect from light
CAS No.84573-16-0
DescriptionPEGylated liposomes containing Rocaglamide (Roc-A). Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective HSF1 activation inhibitor (IC50 ~50 nM). Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also exhibits anti-leukemia activity. Rocaglamide is insoluble in aqueous media. This product is a pre-formulated liposomal version of Rocaglamide which is supplied ready to use in vitro or in vivo. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only.
Lipid compositionPEGylated Liposomes
Liposome Size70-120 nm
Lipid Molar Concentration60 mM
Shelf-lifeAt least 1 month
Encapsulated DrugRocaglamide
Drug concentration4.0 mg/mL (± ~5%)
Inside Buffer292 mM sucrose, 0.5% DPBS (1X)
Outside Buffer292 mM sucrose, 0.5% DPBS (1X)
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