Storage | 2 °C to 8 °C (do not freeze), protect from light |
Description | PEGylated liposomes containing Hsp90 inhibitor Tanespimycin (17-AAG). Tanespimycin exhibits 100-fold higher binding affinity to HSP90 derived from tumor cells vs normal cells, and induces apoptosis, necrosis, autophagy, and mitophagy. Tanespimycin is insoluble in aqueous media. This product is a pre-formulated liposomal version of Tanespimycin which is supplied ready to use in vitro or in vivo. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only. |
Lipid composition | PEGylated Liposomes |
Liposome Size | 70-120 nm |
Lipid Molar Concentration | 60 mM |
Shelf-life | At least 1 month |
Encapsulated Drug | Tanespimycin |
Drug concentration | 2.5 mg/mL |
Inside Buffer | 300 mM sucrose |
Outside Buffer | 300 mM sucrose |
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×Product Name | Catalog | Lipid composition | Liposome Size | Price |
---|---|---|---|---|
Clipos™ Tanespimycin (17-AAG) Encapsulated Liposomes | CDEPG-32 | PEGylated Liposomes | 70-120 nm | $1380 |
Clipos™ Tanespimycin (17-AAG) Encapsulated Liposomes | CDEPG-34 | HSPC/Chol/DSPE-mPEG2000 (56.2/38.5/5.3 molar ratio) | 70-120 nm | $2200 |
Clipos™ Tanespimycin (17-AAG) Encapsulated Liposomes | CDEPG-21 | PEGylated Liposomes | 70-120 nm | $2300 |
Clipos™ Tanespimycin (17-AAG) Encapsulated Liposomes | CDEPG-31 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Tanespimycin (17-AAG) Encapsulated Liposomes | CDEPG-20 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Tanespimycin (17-AAG) Encapsulated Liposomes | CDEPG-22 | PEGylated Liposomes | 70-120 nm | $4500 |
Clipos™ Tanespimycin (17-AAG) Encapsulated Liposomes | CDEPG-33 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Tanespimycin (17-AAG) Encapsulated Liposomes | CDEPG-24 | PEGylated Liposomes | 70-120 nm | $4500 |
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