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Clipos™ Tanespimycin (17-AAG) Encapsulated Liposomes


Catalog:CDEPG-29

Unit Size
Price
$2200

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Storage2 °C to 8 °C (do not freeze), protect from light
DescriptionPEGylated liposomes containing Hsp90 inhibitor Tanespimycin (17-AAG). Tanespimycin exhibits 100-fold higher binding affinity to HSP90 derived from tumor cells vs normal cells, and induces apoptosis, necrosis, autophagy, and mitophagy. Tanespimycin is insoluble in aqueous media. This product is a pre-formulated liposomal version of Tanespimycin which is supplied ready to use in vitro or in vivo. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only.
Lipid compositionPEGylated Liposomes
Liposome Size70-120 nm
Lipid Molar Concentration60 mM
Shelf-lifeAt least 1 month
Encapsulated DrugTanespimycin
Drug concentration2.5 mg/mL
Inside Buffer300 mM sucrose
Outside Buffer300 mM sucrose
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