Storage | 2 °C to 8 °C (do not freeze), protect from light |
CAS No. | 1693758-51-8 |
Description | PEGylated liposomes containing PI3Kγ inhibitor Eganelisib (IPI-549). Eganelisib (IPI-549) is a potent and selective PI3Kγ inhibitor (IC50 16 nM) which is reported to exhibit more than 100-fold selectivity over other lipid and protein kinases and potentiate immunotherapy with immune checkpoint inhibitors in mice. IPI-549 is insoluble in aqueous media. This product is a pre-formulated liposomal version of IPI-549 which is supplied ready to use in vitro or in vivo. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only. |
Lipid composition | PEGylated Liposomes |
Liposome Size | 70-120 nm |
Lipid Molar Concentration | 60 mM |
Shelf-life | At least 1 month |
Encapsulated Drug | Eganelisib |
Drug concentration | 2.0 mg/mL |
Inside Buffer | 292 mM sucrose, 0.5% DPBS (1X) |
Outside Buffer | 292 mM sucrose, 0.5% DPBS (1X) |
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×Product Name | Catalog | Lipid composition | Liposome Size | Price |
---|---|---|---|---|
Clipos™ Eganelisib (IPI-549) Encapsulated Liposomes | CDEPG-28 | PEGylated Liposomes | 70-120 nm | $1380 |
Clipos™ Eganelisib (IPI-549) Encapsulated Liposomes | CDEPG-35 | HSPC/Chol/DSPE-mPEG2000 (56.2/38.5/5.3 molar ratio) | 70-120 nm | INQUIRY |
Clipos™ Eganelisib (IPI-549) Encapsulated Liposomes | CDEPG-29 | PEGylated Liposomes | 70-120 nm | $2200 |
Clipos™ Eganelisib (IPI-549) Encapsulated Liposomes | CDEPG-31 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Eganelisib (IPI-549) Encapsulated Liposomes | CDEPG-33 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Eganelisib (IPI-549) Encapsulated Liposomes | CDEPG-21 | PEGylated Liposomes | 70-120 nm | $2300 |
Clipos™ Eganelisib (IPI-549) Encapsulated Liposomes | CDEPG-20 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Eganelisib (IPI-549) Encapsulated Liposomes | CDEPG-22 | PEGylated Liposomes | 70-120 nm | $4500 |
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