Storage | 2 °C to 8 °C (do not freeze), protect from light |
CAS No. | 53123-88-9 |
Description | PEGylated liposomes containing mTOR inhibitor Rapamycin (Sirolimus; AY-22989). Rapamycin is a potent and specific inhibitor of mTOR (IC50 0.1 nM, HEK293 cells). Rapamycin binds to FKBP12 and is an allosteric inhibitor of mTORC1. Rapamycin is an immunosuppressant and activator of autophagy. Rapamycin is insoluble in aqueous media. This product is a pre-formulated liposomal version of Rapamycin which is supplied ready to use in vitro or in vivo. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only. |
Lipid composition | PEGylated Liposomes |
Liposome Size | 70-120 nm |
Lipid Molar Concentration | 60 mM |
Shelf-life | At least 1 month |
Encapsulated Drug | Rapamycin |
Drug concentration | 3.3 mg/mL |
Inside Buffer | 292 mM sucrose, 0.5% DPBS (1X) |
Outside Buffer | 292 mM sucrose, 0.5% DPBS (1X) |
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×Product Name | Catalog | Lipid composition | Liposome Size | Price |
---|---|---|---|---|
Clipos™ Rapamycin (Sirolimus) Encapsulated Liposomes | CDEPG-21 | PEGylated Liposomes | 70-120 nm | $2300 |
Clipos™ Rapamycin (Sirolimus) Encapsulated Liposomes | CDEPG-28 | PEGylated Liposomes | 70-120 nm | $1380 |
Clipos™ Rapamycin (Sirolimus) Encapsulated Liposomes | CDEPG-03 | PEGylated liposomes | 70-120 nm | INQUIRY |
Clipos™ Rapamycin (Sirolimus) Encapsulated Liposomes | CDEPG-29 | PEGylated Liposomes | 70-120 nm | $2200 |
Clipos™ Rapamycin (Sirolimus) Encapsulated Liposomes | CDEPG-32 | PEGylated Liposomes | 70-120 nm | $1380 |
Clipos™ Rapamycin (Sirolimus) Encapsulated Liposomes | CDEPG-20 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Rapamycin (Sirolimus) Encapsulated Liposomes | CDEPG-31 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Rapamycin (Sirolimus) Encapsulated Liposomes | CDEPG-24 | PEGylated Liposomes | 70-120 nm | $4500 |
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