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Clipos™ Rapamycin (Sirolimus) Encapsulated Liposomes


Catalog:CDEPG-23

Unit Size:

INQUIRY Datasheet

Storage2 °C to 8 °C (do not freeze), protect from light
CAS No.53123-88-9
DescriptionPEGylated liposomes containing mTOR inhibitor Rapamycin (Sirolimus; AY-22989). Rapamycin is a potent and specific inhibitor of mTOR (IC50 0.1 nM, HEK293 cells). Rapamycin binds to FKBP12 and is an allosteric inhibitor of mTORC1. Rapamycin is an immunosuppressant and activator of autophagy. Rapamycin is insoluble in aqueous media. This product is a pre-formulated liposomal version of Rapamycin which is supplied ready to use in vitro or in vivo. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only.
Lipid compositionPEGylated Liposomes
Liposome Size70-120 nm
Lipid Molar Concentration60 mM
Shelf-lifeAt least 1 month
Encapsulated DrugRapamycin
Drug concentration3.3 mg/mL
Inside Buffer292 mM sucrose, 0.5% DPBS (1X)
Outside Buffer292 mM sucrose, 0.5% DPBS (1X)
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