Storage | 2 °C to 8 °C (do not freeze) |
CAS No. | 2068-78-2 |
Description | Vincristine (NSC-67574) sulfate is an antitumor vinca alkaloid which inhibits microtubule polymerization. and binds tubulin. Vincristine (NSC-67574) sulfate binds tubulin (IC50 32 μM) and causes cell cycle arrest (metaphase) and induces apoptosis. This product is a pre-formulated liposomal version of Vincristine (NSC-67574) sulfate which is supplied ready to use in vitro or in vivo. The liposomes are PEGylated for optimal in vivo performance; the lipid composition of the liposomes is the same as Doxil. For preclinical research use only. |
Lipid composition | HSPC/Chol/DSPE-mPEG2000 (56.2/38.5/5.3 molar ratio) |
Liposome Size | 70-120 nm |
Lipid Molar Concentration | 26.4 mM |
Shelf-life | At least 3 months |
Encapsulated Drug | Vincristine |
Drug concentration | 2.0 mg/mL |
Inside Buffer | 250 mM ammonium sulfate, pH 5.5 |
Outside Buffer | DPBS (1X), pH 7.4 |
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×Product Name | Catalog | Lipid composition | Liposome Size | Price |
---|---|---|---|---|
Clipos™ Vincristine (NSC-67574) Encapsulated Liposomes | CDEPG-21 | PEGylated Liposomes | 70-120 nm | $2300 |
Clipos™ Vincristine (NSC-67574) Encapsulated Liposomes | CDEPG-23 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Vincristine (NSC-67574) Encapsulated Liposomes | CDEPG-24 | PEGylated Liposomes | 70-120 nm | $4500 |
Clipos™ Vincristine (NSC-67574) Encapsulated Liposomes | CDEPG-03 | PEGylated liposomes | 70-120 nm | INQUIRY |
Clipos™ Vincristine (NSC-67574) Encapsulated Liposomes | CDEPG-27 | PEGylated Liposomes | 70-120 nm | $4500 |
Clipos™ Vincristine (NSC-67574) Encapsulated Liposomes | CDEPG-25 | PEGylated Liposomes | 70-120 nm | $4500 |
Clipos™ Vincristine (NSC-67574) Encapsulated Liposomes | CDEPG-31 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Vincristine (NSC-67574) Encapsulated Liposomes | CDEPG-33 | PEGylated Liposomes | 70-120 nm | INQUIRY |
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