Storage | 2 °C to 8 °C (do not freeze) |
Description | PEGylated liposomes containing HDAC inhibitor Belinostat (PXD101, NSC726630, PX-105684). Belinostat is a histone deacetylase inhibitor (HDACi) with reported IC50 of 27 nM (cell-free assay) and has been reported to induce autophagy and possess activity in cisplatin-resistant tumors. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only. |
Lipid composition | PEGylated Liposomes |
Liposome Size | 70-120 nm |
Lipid Molar Concentration | 60 mM |
Shelf-life | 1 month |
Encapsulated Drug | Belinostat (PXD101, NSC726630, PX-105684) |
Drug concentration | 3.1 mg/mL |
Inside Buffer | 292 mM sucrose, 0.5% DPBS (1X) |
Outside Buffer | 292 mM sucrose, 0.5% DPBS (1X) |
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×Product Name | Catalog | Lipid composition | Liposome Size | Price |
---|---|---|---|---|
Clipos™ Belinostat (PXD101) Encapsulated Liposomes | CDEPG-28 | PEGylated Liposomes | 70-120 nm | $1380 |
Clipos™ Belinostat (PXD101) Encapsulated Liposomes | CDEPG-29 | PEGylated Liposomes | 70-120 nm | $2200 |
Clipos™ Belinostat (PXD101) Encapsulated Liposomes | CDEPG-35 | HSPC/Chol/DSPE-mPEG2000 (56.2/38.5/5.3 molar ratio) | 70-120 nm | INQUIRY |
Clipos™ Belinostat (PXD101) Encapsulated Liposomes | CDEPG-20 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Belinostat (PXD101) Encapsulated Liposomes | CDEPG-25 | PEGylated Liposomes | 70-120 nm | $4500 |
Clipos™ Belinostat (PXD101) Encapsulated Liposomes | CDEPG-34 | HSPC/Chol/DSPE-mPEG2000 (56.2/38.5/5.3 molar ratio) | 70-120 nm | $2200 |
Clipos™ Belinostat (PXD101) Encapsulated Liposomes | CDEPG-03 | PEGylated liposomes | 70-120 nm | INQUIRY |
Clipos™ Belinostat (PXD101) Encapsulated Liposomes | CDEPG-32 | PEGylated Liposomes | 70-120 nm | $1380 |
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