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Clipos™ Belinostat (PXD101) Encapsulated Liposomes


Catalog:CDEPG-33

Unit Size:

INQUIRY Datasheet

Storage2 °C to 8 °C (do not freeze)
DescriptionPEGylated liposomes containing HDAC inhibitor Belinostat (PXD101, NSC726630, PX-105684). Belinostat is a histone deacetylase inhibitor (HDACi) with reported IC50 of 27 nM (cell-free assay) and has been reported to induce autophagy and possess activity in cisplatin-resistant tumors. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only.
Lipid compositionPEGylated Liposomes
Liposome Size70-120 nm
Lipid Molar Concentration60 mM
Shelf-life1 month
Encapsulated DrugBelinostat (PXD101, NSC726630, PX-105684)
Drug concentration3.1 mg/mL
Inside Buffer292 mM sucrose, 0.5% DPBS (1X)
Outside Buffer292 mM sucrose, 0.5% DPBS (1X)
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