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Clipos™ Nirmatrelvir (PF-07321332) Encapsulated Liposomes


Catalog:CDEPG-31

Unit Size:

INQUIRY Datasheet

Storage2 °C to 8 °C (do not freeze)
CAS No.2628280-40-8
DescriptionPEGylated liposomes containing SARS-CoV-2 Mpro inhibitor Nirmatrelvir (PF-07321332). Nirmatrelvir (PF-07321332) is a reversible covalent inhibitor of the SARS-CoV-2 main protease (Mpro, also referred to as 3CL protease or 3CLpro) that binds to the catalytic cysteine (Cys145) and has a reported ki of 3.11 nM. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only.
Lipid compositionPEGylated Liposomes
Liposome Size70-120 nm
Lipid Molar Concentration60 mM
Shelf-lifeAt least 1 month
Encapsulated DrugNirmatrelvir
Drug concentration10.0 mg/mL (± ~5%)
Inside Buffer292 mM sucrose, 0.5% DPBS (1X)
Outside Buffer292 mM sucrose, 0.5% DPBS (1X)
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