Storage | 2 °C to 8 °C (do not freeze) |
CAS No. | 2628280-40-8 |
Description | PEGylated liposomes containing SARS-CoV-2 Mpro inhibitor Nirmatrelvir (PF-07321332). Nirmatrelvir (PF-07321332) is a reversible covalent inhibitor of the SARS-CoV-2 main protease (Mpro, also referred to as 3CL protease or 3CLpro) that binds to the catalytic cysteine (Cys145) and has a reported ki of 3.11 nM. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only. |
Lipid composition | PEGylated Liposomes |
Liposome Size | 70-120 nm |
Lipid Molar Concentration | 60 mM |
Shelf-life | At least 1 month |
Encapsulated Drug | Nirmatrelvir |
Drug concentration | 10.0 mg/mL (± ~5%) |
Inside Buffer | 292 mM sucrose, 0.5% DPBS (1X) |
Outside Buffer | 292 mM sucrose, 0.5% DPBS (1X) |
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×Product Name | Catalog | Lipid composition | Liposome Size | Price |
---|---|---|---|---|
Clipos™ Nirmatrelvir (PF-07321332) Encapsulated Liposomes | CDEPG-22 | PEGylated Liposomes | 70-120 nm | $4500 |
Clipos™ Nirmatrelvir (PF-07321332) Encapsulated Liposomes | CDEPG-23 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Nirmatrelvir (PF-07321332) Encapsulated Liposomes | CDEPG-24 | PEGylated Liposomes | 70-120 nm | $4500 |
Clipos™ Nirmatrelvir (PF-07321332) Encapsulated Liposomes | CDEPG-28 | PEGylated Liposomes | 70-120 nm | $1380 |
Clipos™ Nirmatrelvir (PF-07321332) Encapsulated Liposomes | CDEPG-32 | PEGylated Liposomes | 70-120 nm | $1380 |
Clipos™ Nirmatrelvir (PF-07321332) Encapsulated Liposomes | CDEPG-34 | HSPC/Chol/DSPE-mPEG2000 (56.2/38.5/5.3 molar ratio) | 70-120 nm | $2200 |
Clipos™ Nirmatrelvir (PF-07321332) Encapsulated Liposomes | CDEPG-33 | PEGylated Liposomes | 70-120 nm | INQUIRY |
Clipos™ Nirmatrelvir (PF-07321332) Encapsulated Liposomes | CDEPG-03 | PEGylated liposomes | 70-120 nm | INQUIRY |
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