| CAS No. | 170632-47-0 |
| Description | PEGylated liposomes containing HIF-1α inhibitor Lificiguat (YC-1). Lificiguat (YC-1) is an inhibitor of Hypoxia-inducible factor-1 alpha (HIF-1 alpha). YC-1 also activates soluble guanylyl cyclase (sGC) in (NO)-independent manner. Lificiguat (YC-1) is insoluble in aqueous media. This product is a pre-formulated liposomal version of Lificiguat which is supplied ready to use in vitro or in vivo. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only. |
| Lipid composition | PEGylated Liposomes |
| Liposome Size | 70-120 nm |
| Lipid Molar Concentration | 60 mM |
| Shelf-life | At least 1 month |
| Encapsulated Drug | Lificiguat |
| Drug concentration | 2.5 mg/mL |
| Inside Buffer | 292 mM sucrose, 0.5% DPBS (1X) |
| Outside Buffer | 292 mM sucrose, 0.5% DPBS (1X) |
| Storage | 2 °C to 8 °C (do not freeze), protect from light |
| Product Name | Catalog | Lipid composition | Liposome Size | Price |
|---|---|---|---|---|
| Clipos™ Lificiguat (YC-1) Encapsulated Liposomes | CDEPG-32 | PEGylated Liposomes | 70-120 nm | $1380 |
| Clipos™ Lificiguat (YC-1) Encapsulated Liposomes | CDEPG-31 | PEGylated Liposomes | 70-120 nm | INQUIRY |
| Clipos™ Lificiguat (YC-1) Encapsulated Liposomes | CDEPG-25 | PEGylated Liposomes | 70-120 nm | $4500 |
| Clipos™ Lificiguat (YC-1) Encapsulated Liposomes | CDEPG-29 | PEGylated Liposomes | 70-120 nm | $2200 |
| Clipos™ Lificiguat (YC-1) Encapsulated Liposomes | CDEPG-34 | HSPC/Chol/DSPE-mPEG2000 (56.2/38.5/5.3 molar ratio) | 70-120 nm | $2200 |
| Clipos™ Lificiguat (YC-1) Encapsulated Liposomes | CDEPG-23 | PEGylated Liposomes | 70-120 nm | INQUIRY |
| Clipos™ Lificiguat (YC-1) Encapsulated Liposomes | CDEPG-20 | PEGylated Liposomes | 70-120 nm | INQUIRY |
| Clipos™ Lificiguat (YC-1) Encapsulated Liposomes | CDEPG-27 | PEGylated Liposomes | 70-120 nm | $4500 |
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Datasheet